The most significant factor showing that countries are economically developed is the level of technology they produce. Technology, on the other hand, is the application of knowledge produced theoretically through scientific research. In this context, there is a clear connection between the level of economic development and welfare and the point reached in science. The resources that countries allocate to science and research activities are increasing every year, and the effective use of these resources plays a critical role in increasing the welfare level of these countries. This study reveals the effect of the university investment budget, which constitutes an essential part of the financial resources allocated to research and development activities in Turkey, on the research performance of universities. Multiple regression analysis was used to achieve the aim outlined in this thesis. The number of publications per lecturer published in AHCI, SSCI, SCI, and SCI-Expanded indexed journals and the number of Web of Science publications citations were used as dependent variables to represent research performance. The rate of investment budget spent on R&D was used as an independent variable to represent R&D expenditures. In addition, the number of lecturers and the number of YÖK 100/2000 Project doctoral scholars were included in the models as control variables. It was concluded that R&D expenditures affect research performance positively.