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Estudio de la actividad bactericida de las AgNP y AuNP en solución y soportadas en microesferas de PHB

Authors: Grajales Velázquez, Jair;

Estudio de la actividad bactericida de las AgNP y AuNP en solución y soportadas en microesferas de PHB

Abstract

"Las bacterias multidrogo resistentes (MDR), siguen siendo un desafío en la salud pública, el número de infecciones causadas por estas ha ido aumentando a nivel mundial, esta resistencia representa un desafío para muchos medicamentos. Los recientes avances en la nanotecnología nos permiten desarrollar nuevas formulaciones basadas en distintos tipos de nanopartículas. Éstas pueden ofrecer una solución prometedora en especial las de plata y oro, se ha estudiado la capacidad antimicrobiana y comprobado su efecto contra distintas cepas bacterianas. Una forma para extender aún más las aplicaciones antimicrobianas de estos metales es mediante la incorporación como nanopartículas en el biopolímero poli-ß-hidroxibutirato (PHB). En el presente trabajo se sintetizaron nanopartículas mediante reducción química, plata de 74.3 nm y 114.1 nm, oro de 76.5 nm y microesferas de PHB por el método físico dando un tamaño de 172.3 nm. Las partículas metálicas fueron caracterizadas por UV-Vis, AFM, DLS y potencial zeta, mientras que la elaboración de la película de PHB se hizo mediante la cuantificación del polímero depositado en el sustrato, perfilometria y AFM."

Country
Mexico
Keywords

Agentes antibacteriales, Area::BIOLOGÍA Y QUÍMICA, Resistencia a drogas en microorganismos, Ingeniería biomédica, Nanopartículas--Uso terapéutico

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green