The study aims to assess the psychological factors associated with burnout among nurses. The Study trying to test these hypotheses: The researcher predict higher rates in total score of burnout at significant level ( ) among the Nurses. The researcher predict higher rates of stressed nurses with significant statistical level at ( ) that positively related to the total score of burnout. The researcher predicts higher rates of social support that positively related with the total score of burnout level at significant level ( ). The researcher predict no significant statistical differences at level () in the burnout total score due to the sex of the nurse. The researcher predict no significant statistical differences at significant level () in the burnout total score due to the age of the nurse. The researcher predict no significant statistical differences at significant level () in the burnout total score due to the educational level of the nurse. The researcher predict no significant statistical differences at significant level () in the burnout total score due to the Nurses' experiences. The researcher predict no significant statistical differences at significant level () in the burnout total score due to the working place (hospitals) of the nurses. In order to test these hypotheses the descriptive analysis style followed, the sample consist of 122 nurse distributed in 5 hospitals, The selected Nursing are classified under the various types of work fields like Neonatal intensive care unit, The artificial kidney unit, The cancer unit, The female medical department, chest unit department, emergency department, burn intensive care unit, obstetric department, medical child departments, ophthalmology hospital, and others. The tools used in the study: Burnout inventory checklist, Work stress checklist, Social support checklist, Personal data sheet (sex, age, years of experience, place of work). Statistical methods which followed in the study were: Frequencies and Percentile ,Alpha- Cronbach Test for measuring reliability of the items of the questionnaires ,Person correlation coefficients for measuring validity of the items of the questionnaires ,Spearman –Brown Coefficient ,One sample t test ,Independent samples t test ,One way ANOVA. The results of the study : the total score of burnout percentage is 50%,the work stress was 72%, the social support was 70% ,the did total score of burnout percentage did not affected by the variables like sex, age, educational level, place of work, nurses experience at significant level( ). The recommendations of the study are: Improve the management systems, Redesign jobs and reorganize work system according to job description, Improve health safety systems & activate psychological counseling.