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Biodegradable stents and non-biodegradable stents.

Authors: Garg, Scot; Serruys, PWJC (Patrick);

Biodegradable stents and non-biodegradable stents.

Abstract

The introduction of the coronary stent in 1986 was one of the most far-reaching changes in the practice of interventional cardiology since its inception in 1977. Despite all the benefits of the using a metallic drug eluting stent (DES), their limitations have generated interest towards biodegradable technology. These biodegradable stents, which are made of polymers or metal alloys with or without a drug coating, have the potential to scaffold the artery to allow natural healing to take place, and then biodegrade. The development of this technology has been slow, however several biodegradable stents have entered into clinical trials, with many more at the preclinical stage of development. Concurrently conventional metallic DES have tried to address their limitations; in particular they have sought to repair their damaged reputation following concerns over stent thrombosis. Accordingly, stents with a more biocompatible polymer and DES which are polymer-free have been developed, and are currently being evaluated in clinical trials. This article will review the status of biodegradable stents, and these newer DES, during this exciting period in interventional cardiology as technology strives to develop the ideal coronary stent.

Country
Netherlands
Related Organizations
Keywords

Polyesters, Absorbable Implants, Humans, Stents, Prosthesis Design, Coronary Vessels, EMC COEUR-09

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    popularity
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    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
18
Average
Top 10%
Top 10%
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