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Acta Poloniae Pharmaceutica - Drug Research
Article . 2009
Data sources: Europe PubMed Central
Claim

Synthesis of 1,2,4-triazine derivatives as potential anti-anxiety and anti-inflammatory agents.

descriptionPublicationkeyboard_double_arrow_right Article 08 Sep 2009 English Journal:Acta poloniae pharmaceutica, volume 66 (issn: 0001-6837, Copyright policy )
Authors: Pooja, Mullick; Suroor A, Khan; Tauseef, Begum; Surajpal, Verma; Darpan, Kaushik; Ozair, Alam;

pmid: 19702169

Synthesis of 1,2,4-triazine derivatives as potential anti-anxiety and anti-inflammatory agents.

Abstract

A series of 1,2,4-triazine derivatives Va (1-24) and Vb (1-24) were synthesized and evaluated for their anti-anxiety and anti-inflammatory activities. The structures of the synthesized compounds were confirmed on the basis of their spectral data. Many of the triazine compounds were found to possess good activity. Especially, compounds bearing the sulfur atom showed better activity than those bearing the oxygen atom.

Keywords

Structure-Activity Relationship, Anti-Anxiety Agents, Triazines, Anti-Inflammatory Agents, Hydrazones, Animals, Rats

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    		 19
    popularity
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    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Top 10%
Average
gold
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