
pmid: 19648743
handle: 11245/1.312695
The aim of this study was to investigate the antimicrobial activity of vanadium chloroperoxidase (VCPO) reaction products on planktonic and biofilm cells of Streptococcus mutans C180-2. Planktonic and biofilm cells were incubated in a buffered reaction mixture containing VCPO, halide (either chloride or bromide) and hydrogen peroxide, and the killing efficacy was assessed by CFU counts. The enzymatic products formed by VCPO significantly reduced the viability of planktonic and biofilm cells compared to their negative controls and the effect on the biofilm cells was more effective than a 0.2% chlorhexidine digluconate treatment. We conclude that VCPO and its reaction products form a potent antimicrobial system against S. mutans.
Streptococcus mutans, Anti-Infective Agents, Biofilms, Colony Count, Microbial, 610, 540, SDG 6 - Clean Water and Sanitation, Chloride Peroxidase, Plankton
Streptococcus mutans, Anti-Infective Agents, Biofilms, Colony Count, Microbial, 610, 540, SDG 6 - Clean Water and Sanitation, Chloride Peroxidase, Plankton
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