
This is a study of in situ chromosomal hybridization and dot blot and southern blot hybridization using a testis determining factor related probe Y156 in sexually malformed patients. According to the phenotype karyotype analysis and hybridization results of these cases, especially 2 cases with dic (Y) and different breakpoints, we consider that the TDF must be located on YP11.32. The clinical value of Y156 probe is discussed.
DNA-Binding Proteins, Male, Y Chromosome, Disorders of Sex Development, Kruppel-Like Transcription Factors, Humans, Nucleic Acid Hybridization, DNA Probes, Sex Chromosome Aberrations, Transcription Factors
DNA-Binding Proteins, Male, Y Chromosome, Disorders of Sex Development, Kruppel-Like Transcription Factors, Humans, Nucleic Acid Hybridization, DNA Probes, Sex Chromosome Aberrations, Transcription Factors
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