Radioactive nucleic acids-precursors: their potential value as tumor-localizing agents.
Copyright policy )Radioactive nucleic acids-precursors: their potential value as tumor-localizing agents.
The distribution of 125I-uracil and 125I-deoxyuridine in tumor-bearing animals has been studied. 125I-deoxyuridine shows the characteristics of a tumor-scanning agent. The metabolic incorporation by tumors of this DNA-precursor indicates a potential value of this radiocompound for their detection, differentiation and follow-up of their evolution after therapy.
Mice, Inbred C3H, Carcinoma, Hepatocellular, Lymphoma, Non-Hodgkin, Liver Neoplasms, Nucleic Acid Precursors, DNA, Neoplasms, Experimental, Deoxyuridine, Leukemia, Lymphoid, Rats, Iodine Radioisotopes, Mice, Mice, Inbred AKR, Neoplasms, Animals, RNA, Radionuclide Imaging, Uracil, Neoplasm Transplantation
Mice, Inbred C3H, Carcinoma, Hepatocellular, Lymphoma, Non-Hodgkin, Liver Neoplasms, Nucleic Acid Precursors, DNA, Neoplasms, Experimental, Deoxyuridine, Leukemia, Lymphoid, Rats, Iodine Radioisotopes, Mice, Mice, Inbred AKR, Neoplasms, Animals, RNA, Radionuclide Imaging, Uracil, Neoplasm Transplantation
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