To retrospectively analyze the advantages and disadvantages of imaging methods commonly used for diagnosis of gland submandibular diseases.One hundred and eighty-two patients with submandibular gland surgery were retrospectively studied to compare the accuracy rate between preoperative imaging and postoperative diagnosis.The data were analyzed using SAS8.0 software package.Fisher's exact test was used to compare the difference between B type ultrasonography, CT and MRI.Compared with postoperative pathological results,diagnostic accuracy rate of B type ultrasonography, CT and X-ray was 85.34%, 79.66% and 92.31%, respectively. MRI had a higher accuracy rate than B type ultrasonography or CT.(P<0.05).B type ultrasonography, CT and X-ray examination have misdiagnosis especially in submandibular sialadenitis,which is one of the most important causes of misdiagnosis leading to excision of the glands.MRI has higher application value in diagnosis of submandibular gland diseases.