Central venous cannulation is frequently used in patients with serious diseases, although it may be unsuccessful and known to have complications in many cases. It is especially true in more complicated cases e.g. after unsuccessful punctures or cervical operations. With the use of ultrasound control success rate increases, while the chance of the complications decreases. In this prospective study, authors used ultrasound control during jugular vein punction in complicated cases. 56 successful central venous cannulation controlled by ultrasound has been performed since year 2000. This report overviews these cases and the related literature.