[Clinical characteristics of patients with juvenile localized scleroderma].

Qiu-Ning, Sun; Wei, Du; Bin, Hu; Pai, Liu; Xie, Yuan

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Article . 2011

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[Clinical characteristics of patients with juvenile localized scleroderma].

descriptionPublicationkeyboard_double_arrow_right Article 28 Jan 2011Journal:Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, volume 31 (issn: 1000-503X,

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Authors: Qiu-Ning, Sun; Wei, Du; Bin, Hu; Pai, Liu; Xie, Yuan;

pmid: 19317059

[Clinical characteristics of patients with juvenile localized scleroderma].

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Abstract

To investigate the clinical characteristics of juvenile localized scleroderma (JLS).The clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.Of a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as generalized morphea, and 15 (15%) as a mixed subtype. Nine patients (9%) had family histories of rheumatic or autoimmune diseases, while 16 (16%) might be triggered by unknown factors. Totally 84 patients underwent antinuclear antibody tests and 38 patients (45.2%) had positive results.Linear scleroderma are the most frequent subtype of JLS. Localized scleroderma may be associated with some autoimmune-related causes.

Keywords

Male, Adolescent, Infant, Autoimmune Diseases, Scleroderma, Localized, Antibodies, Antinuclear, Child, Preschool, Humans, Female, Child, Retrospective Studies

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