In all European countries, the rates of death were higher in groups of lower socioeconomic status, but the magnitude of the inequalities between groups of higher and lower socioeconomic status was much larger in some countries than in others. Inequalities in mortality were small in some Southern European countries and very large in most countries in the eastern and Baltic regions. These variations among countries appeared to be attributable in part to causes of death related to smoking or alcohol use or amenable to medical intervention. These results imply that there is opportunity to reduce inequalities in mortality. Developing policies and interventions that effectively target the structural and immediate determinants of inequalities in health is an urgent priority for public health research.