Injuries caused by a shotgun belong to the group of less frequent gunshot wounds. Shotguns are usually used to fire multiple pellets, but they are capable of firing single projectiles. Shotgun slug injuries are rare and severe, and fully compareable to those inflicted by high-velocity projectiles. Thanks to great slug's mass and size can create more tissue destruction than the high-velocity missiles. Characteristic ballistic properties of shotgun slugs, their wounding potential and significance in forensic pathology are presented.