gammadelta T cell selection: is anyone useless?

In this issue of Immunity, a study by Jensen et al. (2008) suggests that T cell-receptor engagement during development affects gammadelta T cell polarization toward either interferon-gamma or interleukin-17 production. This might underlie their unique innate ability to regulate inflammation.

Keywords

Mice, T-Lymphocyte Subsets, T-Lymphocytes, Animals, Cell Differentiation, Receptors, Antigen, T-Cell, gamma-delta

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