A short route to alpha-tocopherol.

Liu, Kegang; Chougnet, Antoinette; Woggon, Wolf-D.

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Angewandte Chemie International Edition

Article . 2008

Data sources: Europe PubMed Central

SONAR - Swiss Open Access Repository

Article . 2008

Data sources: SONAR - Swiss Open Access Repository

A short route to alpha-tocopherol.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2008 Switzerland English Publisher:VCHJournal:Angewandte Chemie (International ed. in English), volume 47 (issn: 1521-3773,

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Authors: Liu, Kegang; Chougnet, Antoinette; Woggon, Wolf-D.;

pmid: 18576461

A short route to alpha-tocopherol.

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Abstract

A simple and practical route to alpha-tocopherol (I) is described. The key step is a remarkably diastereoselective domino aldol/oxa-Michael reaction, which is promoted by a proline deriv.

Country

Switzerland

Related Organizations

University of Basel
Switzerland

Keywords

alpha-Tocopherol, Stereoisomerism, Crystallography, X-Ray, Chromatography, High Pressure Liquid

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