The overriding goal of an organized mammography screening program is to offer high level medical care to everyone at a justifiable cost. The following overview will demonstrate how both aspects of screening, quality and cost efficiency, are supported by a fully digital workflow. Digital mammography systems allow for a constant high image quality and repeat examinations due to overexposure or underexposure can be avoided. Dedicated mammography screening workstations with integration of image viewing and reporting enable efficient softcopy reading. Many aspects of the screening workflow, such as double reading, archiving and retrieval of stored films, as well as information exchange between members of the certified team of the screening unit and other physicians involved in the further treatment, are made significantly easier by the presence of image data in digital form.