Immunodominant-peptide recognition: beta testing TCRalphabeta.

In this issue, Ishizuka et al. (2008) define human T cell-receptor recognition of an immunodominant influenza A matrix peptide bound to human leukocyte antigen HLA-A*0201 in atomic detail, raising provocative questions about beta chain function.

Related Organizations

Dana-Farber Cancer Institute
United States

Keywords

Viral Matrix Proteins, HLA-A Antigens, Immunodominant Epitopes, Influenza A virus, Receptors, Antigen, T-Cell, alpha-beta, HLA-A2 Antigen, Humans, Peptides, Peptide Fragments

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