Does histologic chorioamnionitis correspond to clinical chorioamnionitis?
Copyright policy )Does histologic chorioamnionitis correspond to clinical chorioamnionitis?
To evaluate the degree to which histologic chorioamnionitis, a frequent finding in placentas submitted for histopathologic evaluation, correlates with clinical indicators of infection in the mother.A retrospective review was performed on 52 cases with a histologic diagnosis of acute chorioamnionitis from 2,051 deliveries at University Hospital, Newark, from January 2003 to July 2003. Third-trimester placentas without histologic chorioamnionitis (n = 52) served as controls. Cases and controls were selected sequentially. Maternal medical records were reviewed for indicators of maternal infection.Histologic chorioamnionitis was significantly associated with the usage of antibiotics (p = 0.0095) and a higher mean white blood cell count (p = 0.018). The presence of 1 or more clinical indicators was significantly associated with the presence of histologic chorioamnionitis (p = 0.019).Histologic chorioamnionitis is a reliable indicator of infection whether or not it is clinically apparent.
- Rutgers New Jersey Medical School United States
- Rutgers Health United States
Adult, Placenta, Pregnancy Trimester, Third, Infant, Newborn, Gestational Age, Anti-Bacterial Agents, Diagnosis, Differential, Chorioamnionitis, Pregnancy, Case-Control Studies, Humans, Puerperal Infection, Female, Lymphocyte Count, Pregnancy Complications, Infectious, Retrospective Studies
Adult, Placenta, Pregnancy Trimester, Third, Infant, Newborn, Gestational Age, Anti-Bacterial Agents, Diagnosis, Differential, Chorioamnionitis, Pregnancy, Case-Control Studies, Humans, Puerperal Infection, Female, Lymphocyte Count, Pregnancy Complications, Infectious, Retrospective Studies
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