The Authors report their diagnostic experience of 263 patients with abnormal uterine bleeding in peri- and post-menopause. They used a diagnostic procedure which favored the hysteroscopy in first level research: hysteroscopy proved to be a reliable and easily applicable method. In fact it has demonstrated the high incidence of functional pathology (135 cases) and has permitted the histological control of the 3 high risk hyperplasia and of the 15 adenocarcinomatas found in their patients.