Natural killer cells in meningiomas.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1991 Spain English Publisher:Murcia : F. HernándezJournal:Histology and histopathology, volume 6 (issn: 0213-3911,

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Authors: Vaquero, J.; Coca, S.; Pontón, P.; Oya, S.; Arias, A.;

pmid: 1810535

handle: 10201/18238

Natural killer cells in meningiomas.

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Abstract

A monoclonal antibody against the surface marker IOT-10 of natural killer (NK) cells was used to investigate the presence of these cells in a series of twenty intracranial meningiomas. In all of these tumours, IOT-10 positive NK cells were found in small numbers, mainly distributed among the tumor cells. Two recurrent tumors showed a relatively high number of immunostained cells. The data obtained in the present study suggest that a NK-cell-mediated immunological response can occur in meningioma tissue.

Country

Spain

Related Organizations

Autonomous University of Madrid
Spain
University of Murcia
Spain

Keywords

Monoclonal antibody, Adult, Male, Brain Neoplasms, Antibodies, Monoclonal, Middle Aged, :6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.8 - Neurología. Neuropatología. Sistema nervioso [CDU], Immunohistochemistry, Killer Cells, Natural, Lymphocytes, Tumor-Infiltrating, CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.8 - Neurología. Neuropatología. Sistema nervioso, Humans, Female, Natural Killer Cell, Meningioma, Tomography, X-Ray Computed, Biomarkers, Neoplasm Staging

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