
Genotype-dependent behavioral effects were demonstrated in BALB/c, C57BL/6J [Russian character: see text] DBA/2J mice after injections of nootropic drug Noopept. In an elevated plus maze, drug administration induced an increase in the number of enterings into bright arms in BALB/c mice, whereas the opposite effect was observed in C57BL/6J. After the Noopept administration, animals from all the three strains increased the number of active avoidance reactions in stress-inducing slip-funnel test. A significant intensification of exploration behavior was observed in a closed plus-maze in BALB/c and C57BL/6J. The Noopept affected weakly or had no effect on the behavior of DBA/2J mice.
Male, Mice, Inbred BALB C, Behavior, Animal, Dipeptides, Anxiety, Mice, Inbred C57BL, Mice, Species Specificity, Mice, Inbred DBA, Animals, Nootropic Agents
Male, Mice, Inbred BALB C, Behavior, Animal, Dipeptides, Anxiety, Mice, Inbred C57BL, Mice, Species Specificity, Mice, Inbred DBA, Animals, Nootropic Agents
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