Micronized diosmin (Detralex) for vein-related trophic ulcers: European experience.
Copyright policy )Micronized diosmin (Detralex) for vein-related trophic ulcers: European experience.
The paper presents a meta-analysis of 5 large European studies (N - 723) on the micronized diosmin administration to patients with venous trophic ulcers (CEAP class VI). With the use of evidence-based approach, it was shown that micronized diosmin has a statistically significant clinical effect on middle-sized trophic ulcers (5 - 10 cm(2)) that persisted for 6 - 12 months. The study concludes that polyvalent venotonics are an appropriate and valuable addition to complex therapy of complicated chronic venous insufficiency.
- Pirogov Russian National Research Medical University Russian Federation
Adult, Aged, 80 and over, Male, Leg Ulcer, Middle Aged, Atherosclerosis, Varicose Ulcer, Europe, Lower Extremity, Diosmin, Humans, Female, Aged
Adult, Aged, 80 and over, Male, Leg Ulcer, Middle Aged, Atherosclerosis, Varicose Ulcer, Europe, Lower Extremity, Diosmin, Humans, Female, Aged
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