Aim of the study was to confirm depersonalization/derealization in patients with Balkan endemic nephropathy in comparison with other patients on dialysis in Bosnia and Herzegovina within the period 01.01.2000 -31-12-2006. years.Examined were 753 out of 2770 dialyzed patients and they were divided into two groups: those with Balkan endemic nephropathy--BEN group (N+348) and the control group of other diseases N18. Patients were followed-up form 01.01.2000 to 31.12. 2006. when the study was made. It is comparative, cross-sectional study and Questionnaire from the renal Registry of B&H adapted to the mental health and psychological tests--Eizenck's personality characteristics test, Hamilton Depression Rating scale (HDRS) and Mini Mental State evaluation were used.Depersonalization was in BEN group present in 3.50% of cases (chi2 = 70.880, df = 2 p < 0.001), a derealization in 3.75% (chi2 = 117.678, df = 2, p < 0.002) and depersonalization/ derealization in 1.19% of them (chi2 = 218.457, df = 2, p < 0.002). Regression analysis was: y = -0.93x + 14.818, a CI = 95% for Fisher's (Z = -0.995462 to -0.26481). CanFanc r2 = 0.86, P = 0.002 za 87.5% for depersonalization prediction in HRF.In patients on dialyzed treatment in BaH depersonalization sui generis was found in group BEN 3.50% of cases, derealization in 3.57% of them and in group N18 depersonalization in 3.32% of them and possibility to predict depersonalization is 87.50%.