
To establish an HPCE method for the determination of matrine in Matrine Liposome.HPCE was used. The best condition was achieved with a fused silica capillary tube( 150 cm x 75 microm), 0.25 mol/L phosphate buffer (pH 6.8), at constant voltage of 20 kV and temperature at 25 degrees C. The UV detection wavelength was 206 nm.The calibration curve was linear in the range of 0.3-6.025 mg/ml for matrine (0.9995). The average recovery of matrine was 97.3%.This methods is simple, quick, accurate and suitable for the quality control for Matrine Liposome.
Drug Carriers, Plants, Medicinal, Electrophoresis, Capillary, Reproducibility of Results, Fabaceae, Hydrogen-Ion Concentration, Alkaloids, Liposomes, Matrines, Quinolizines, Drugs, Chinese Herbal
Drug Carriers, Plants, Medicinal, Electrophoresis, Capillary, Reproducibility of Results, Fabaceae, Hydrogen-Ion Concentration, Alkaloids, Liposomes, Matrines, Quinolizines, Drugs, Chinese Herbal
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