[Advancements in expression of vascular endothelial growth factor receptors in skin diseases].

Xiao-Hong, Yang; Xiao-Yong, Man; Min, Zheng

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Article . 2010

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[Advancements in expression of vascular endothelial growth factor receptors in skin diseases].

descriptionPublicationkeyboard_double_arrow_right Article 11 May 2010Journal:Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, volume 29 (issn: 1000-503X,

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Authors: Xiao-Hong, Yang; Xiao-Yong, Man; Min, Zheng;

pmid: 17536285

[Advancements in expression of vascular endothelial growth factor receptors in skin diseases].

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Abstract

Vascular endothelial growth factor (VEGF) exerts its biological functions by its specific VEGF receptors (VEGFR), which includes VEGFR-1, VEGFR-2, VEGFR-3, neuropilin-1, and neuropilin-2. These VEGFR distributes in endothelial cells, and are also expressed in normal skin, inflammatory skin diseases, and skin cancers. The VEGF-VEGFR signaling pathway may be a new key target in the management of the skin diseases.

Related Organizations

Women's Hospital School Of Medicine Zhejiang University
China (People's Republic of)

Keywords

Vascular Endothelial Growth Factor A, Receptors, Vascular Endothelial Growth Factor, Animals, Humans, Skin Diseases, Signal Transduction

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