Finding a practical solution for effectively managing facility liquid biowaste is a process of deductive reasoning. Many considerations need to be addressed. The liquid effluent must be characterized to determine required capacity, materials of construction and mode of operation of the biowaste treatment system. Federal, state, local and corporate requirements must be identified to determine system operating parameters. Standard technologies can then be reviewed in order to select the most appropriate unit operation for processing the biowaste. Finally, a validation program is developed to demonstrate the efficacy of the treatment system's intended use. This presentation covers typical considerations in developing the design of a biowaste treatment system and validation of acceptance criteria. Several examples from industrial installations are presented.