Dissolution of gall-stones in vitro.

R P, Modi; T C, Jain; J C, Baid; M, Maheshwari

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Journal of the Indian Medical Association

Article . 1992

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Dissolution of gall-stones in vitro.

descriptionPublicationkeyboard_double_arrow_right Article 21 Jan 1992 English Journal:Journal of the Indian Medical Association, volume 89 (issn: 0019-5847,

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Authors: R P, Modi; T C, Jain; J C, Baid; M, Maheshwari;

pmid: 1748778

Dissolution of gall-stones in vitro.

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Abstract

An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while bile salt (sodium desoxycholate) proved better and clofibrate the best solvent in various concentrations used. In addition 3 stones, one from each patient, were placed in normal saline to serve as control.

Related Organizations

Jawaharlal Nehru Medical College
India

Keywords

Bile Acids and Salts, Cholelithiasis, Heparin, Humans, Clofibrate, In Vitro Techniques

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