This article aims to inform and educate healthcare organizations about one of the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) patient safety goals. The goal allows healthcare institutions to be proactive in identifying risks to patient safety and reduce medical errors at the same time. In this article, you will learn what a Healthcare Failure Mode and Effect Analysis (HFMEA) is, how to pick an appropriate topic, and the steps to follow to be able to implement your own HFMEA. The goal of the HFMEA performed at Massachusetts General Hospital (MGH) was to prevent the misadministration of IV contrast in outpatients in the CT department.