Primary and acquired drug resistance in childhood tuberculosis.

S, Khalilzadeh; M R, Boloorsaz; A, Safavi; P, Farnia; A A, Velayati

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Eastern Mediterranea...arrow_drop_down

Eastern Mediterranean Health Journal

Article . 2007

Data sources: Europe PubMed Central

Primary and acquired drug resistance in childhood tuberculosis.

descriptionPublicationkeyboard_double_arrow_right Article 23 Mar 2007 English Journal:Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, volume 12 (issn: 1020-3397,

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Authors: S, Khalilzadeh; M R, Boloorsaz; A, Safavi; P, Farnia; A A, Velayati;

pmid: 17333839

Primary and acquired drug resistance in childhood tuberculosis.

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Abstract

This study determined the resistance pattern of Mycobacterium tuberculosis to 4 first-line anti-tuberculosis drugs in children with pulmonary tuberculosis at the Iranian National Research Institute of Tuberculosis and Lung Diseases from 1999 to 2004. There were 350 children with positive cultures over the study period: 7 (2%) were resistant to at least one of the 4 anti-tuberculosis drugs. Primary resistance was detected in 4 cases and secondary resistance in 3 cases. Most cases (6) were among Afghan refugees. Resistance to rifampicin both in primary and secondary resistances was high, showing that children in the Islamic Republic of Iran face the threat of drug-resistant tuberculosis transmission.

Related Organizations

Masih Daneshvari Hospital
Iran (Islamic Republic of)

Keywords

Male, Refugees, Gastric Juice, Adolescent, Afghanistan, Antitubercular Agents, Sputum, Child Welfare, Microbial Sensitivity Tests, Iran, Population Surveillance, Isoniazid, Prevalence, Streptomycin, Humans, Female, Rifampin, Child, Ethambutol, Retrospective Studies

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