
The patient is a 31-year-old man who was suffering from hyperthyroidism and left hemothorax. His serum HCG level was extremely elevated and chest X-ray showed a mass shadow of anterior mediastinum and bilateral multiple intrapulmonary metastasis. Our clinical diagnosis was primary HCG-producing germ cell carcinoma of mediastinum and immediately administered CDDP and VP-16. Chemotherapy was effective and tumor extirpation was carried out for mediastinum and lungs by median sternotomy. All of the resected specimen showed no cancer cells and 4 years have passed with no evidence of recurrence. Aggressive surgical approach is indicated for mediastinal germ cell carcinoma accompanied with intrapulmonary metastasis when chemotherapy is effective.
Adult, Male, Lung Neoplasms, Neoplasms, Germ Cell and Embryonal, Vinblastine, Chorionic Gonadotropin, Combined Modality Therapy, Mediastinal Neoplasms, Bleomycin, Antineoplastic Combined Chemotherapy Protocols, Dactinomycin, Humans, Cisplatin
Adult, Male, Lung Neoplasms, Neoplasms, Germ Cell and Embryonal, Vinblastine, Chorionic Gonadotropin, Combined Modality Therapy, Mediastinal Neoplasms, Bleomycin, Antineoplastic Combined Chemotherapy Protocols, Dactinomycin, Humans, Cisplatin
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