This thesis explores a new approach to building data-parallel accelerators that is based on simplifying the instruction set, microarchitecture, and programming methodology for a vector-thread architecture. The thesis begins by categorizing regular and irregular data-level parallelism (DLP), before presenting several architectural design patterns for data-parallel accelerators including the multiple-instruction multiple-data (MIMD) pattern, the vector single-instruction multiple-data (vector-SIMD) pattern, the single-instruction multiple-thread (SIMT) pattern, and the vector-thread (VT) pattern. Our recently proposed VT pattern includes many control threads that each manage their own array of microthreads. The control thread uses vector memory instructions to efficiently move data and vector fetch instructions to broadcast scalar instructions to all microthreads. These vector mechanisms are complemented by the ability for each microthread to direct its own control flow. In this thesis, I introduce various techniques for building simplified instances of the VT pattern. I propose unifying the VT control-thread and microthread scalar instruction sets to simplify the microarchitecture and programming methodology. I propose a new single-lane VT microarchitecture based on minimal changes to the vector-SIMD pattern.