[Anticoagulant activity of sulfated polysaccharides].

N N, Drozd; G E, Bannikova; V A, Makarov; V P, Varlamov

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Экспериментальная и ...arrow_drop_down

Экспериментальная и клиническая фармакология

Article . 2007

Data sources: Europe PubMed Central

[Anticoagulant activity of sulfated polysaccharides].

descriptionPublicationkeyboard_double_arrow_right Article 20 Feb 2007 Russian Journal:Eksperimental'naia i klinicheskaia farmakologiia, volume 69 (issn: 0869-2092,

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Authors: N N, Drozd; G E, Bannikova; V A, Makarov; V P, Varlamov;

pmid: 17209466

[Anticoagulant activity of sulfated polysaccharides].

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Abstract

The paper reviews published data on the chemical structure of sulfated polysaccharides of animal, plant, and microbial origin as well as synthetic or semi-synthetic derivatives, and on the anticoagulant activity of these compounds in vitro and in vivo. The influence of sulfated polysaccharides on the plasma and cell hemostasis links is considered. Relationships between the structure and activity and the mechanisms of action are discussed.

Keywords

Hemostasis, Polysaccharides, Sulfates, Animals, Anticoagulants, Humans

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