
The paper analyzes data of an experimental study of the efficacy of antiviral agents (amantadine, remantadine, ozeltamivir, zanamivir, arbidol, ribavirin) in the cultured cells and on a model of murine influenza pneumonia against influenza A viruses subtype H5N1. It also gives data on their use in the treatment of human beings during avian influenza outbreak. The mechanism of action of the agents, pharmacokinetics, adverse reactions, and their potential resistance are considered.
Indoles, Influenza A Virus, H5N1 Subtype, Sulfides, Virus Replication, Antiviral Agents, Cell Line, Disease Models, Animal, Mice, Oseltamivir, Rimantadine, Orthomyxoviridae Infections, Ribavirin, Amantadine, Animals, Humans, Zanamivir
Indoles, Influenza A Virus, H5N1 Subtype, Sulfides, Virus Replication, Antiviral Agents, Cell Line, Disease Models, Animal, Mice, Oseltamivir, Rimantadine, Orthomyxoviridae Infections, Ribavirin, Amantadine, Animals, Humans, Zanamivir
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