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[Effect of glaucocalyxin A on level of Th1/Th2 type cytokines in mice].

Authors: Zi-jun, Chen; Yun-sen, Li; Ji-yan, Zhou; Zheng-tao, Wang;

[Effect of glaucocalyxin A on level of Th1/Th2 type cytokines in mice].

Abstract

To research the effect of glaucocalyxin A (GLA) on the level of Th1/Th2 type cytokines in mice.By using flow cytometer with CBA software to detect Th1/Th2 type cytokines.GLA had insighificant inhibitory effects on Th1 and Th2 cytokines (IL-2, IFN-gamma,TNF-alpha, IL-4 and IL-5) induced by ConA, in which more potential on cytokines from Th1 than those of from Th2 were displayed. However, GLA could produce inhibition on IL-2, IFN-gamma and TNF-alpha and acceleration on IL-4 and IL-5.Immunosuppressive effect of GLA is related to the influence the level of Th1/Th2 type cytokines.

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Keywords

Male, Mice, Inbred BALB C, Plants, Medicinal, Tumor Necrosis Factor-alpha, Th1 Cells, Interferon-gamma, Mice, Th2 Cells, Isodon, Animals, Cytokines, Interleukin-2, Female, Interleukin-4, Interleukin-5, Diterpenes, Kaurane, Drugs, Chinese Herbal

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citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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