Transcriptional slippage in mxiE controls transcription and translation of the downstream mxiD gene, which encodes a component of the Shigella flexneri type III secretion apparatus.
Copyright policy )Transcriptional slippage in mxiE controls transcription and translation of the downstream mxiD gene, which encodes a component of the Shigella flexneri type III secretion apparatus.
The Shigella flexneri transcription activator MxiE is produced by transcriptional slippage from two overlapping open reading frames. By using plasmids encoding a mxiD-lacZ translational fusion, we showed that transcriptional slippage in mxiE influences both transcription and translation of the downstream mxiD gene encoding an essential component of the type III secretion apparatus.
- Institut Pasteur France
DNA-Binding Proteins, Bacterial Proteins, Transcription, Genetic, Protein Biosynthesis, Frameshifting, Ribosomal, Gene Expression Regulation, Bacterial, Bacterial Outer Membrane Proteins, Shigella flexneri, Transcription Factors
DNA-Binding Proteins, Bacterial Proteins, Transcription, Genetic, Protein Biosynthesis, Frameshifting, Ribosomal, Gene Expression Regulation, Bacterial, Bacterial Outer Membrane Proteins, Shigella flexneri, Transcription Factors
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