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The function of gammadelta T cells in innate immunity.

Authors: Willi K, Born; Christopher L, Reardon; Rebecca L, O'Brien;

The function of gammadelta T cells in innate immunity.

Abstract

Many researchers believe that gammadelta T lymphocytes belong somewhere 'in-between' the innate and adaptive immune systems. Recent studies strongly emphasize the innate features and functions of these cells, including the use of germline elements of the T cell receptor for ligand recognition, segregation into functionally specialized cell populations in correlation with T cell receptor variable gene or protein expression, interactions with cells of the innate system at many levels and, the latest addition, the ability to present antigen. Thus, at present, much evidence suggests that gammadelta T cells function in an innate manner, although they are arguably the most complex and advanced cellular representatives of the innate immune system.

Related Organizations
Keywords

T-Lymphocyte Subsets, Leukocytes, Animals, Humans, Receptors, Antigen, T-Cell, gamma-delta, Dendritic Cells, Immunity, Innate

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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
160
Top 10%
Top 10%
Top 1%
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