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[Hereditary breast cancer].

Authors: Pål, Møller; Lovise, Maehle; Jaran, Apold;

[Hereditary breast cancer].

Abstract

Norwegian health care for women at risk of inherited breast cancer conforms with the European consensus guidelines published in 1999 and the Norwegian legislation regulating the use of predictive genetic testing. This paper represents a consensus between all medical genetic institutions in Norway handling inherited breast cancer through the Norwegian Group on Inherited Cancer. It is an update based on new knowledge, the structure of our health service and locally available technology and health care resources. The indications for referring patients to genetic testing are maintained. The demonstration of local founder BRCA1 mutations has been used to develop a high capacity for testing for these mutations. Mutation carriers should be offered annual MRI of the breasts for early diagnosis. Oophorectomy at end of childbearing ages is advocated in BRCA mutation carriers and breast-ovarian kindreds. The clinical geneticists have the role of coordinating health service to those in need, and are required to collaborate to present the empirical results of the effects of the interventions.

Keywords

Norway, Genes, BRCA2, Genes, BRCA1, Breast Neoplasms, Risk Factors, Mutation, Practice Guidelines as Topic, Humans, Female, Genetic Predisposition to Disease, Genetic Testing

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
Published in a Diamond OA journal