Molecular pathology of ovarian cancer.
Molecular pathology of ovarian cancer.
Ovarian cancer is the leading cause of death among women with gynecologic malignancies. Epithelial tumors typically constitute 80-90% of ovarian malignancies and are classified primarily as serous, mucinous, endometrioid or clear cell. Current data indicate that each of these histologic subtypes is associated with distinct morphologic and molecular genetic alterations. We describe such genetic alterations with specific reference to histologic subtypes.
- University of Florence Italy
- University of Siena Italy
Histological subtype, Ovarian cancer, Cystadenoma, Mucinous, Humans, Histological subtypes; Oncogenes; Ovarian cancer, Neoplasms, Glandular and Epithelial, Oncogene, Ovarian Neoplasms, Retinoblastoma-Like Protein p130, Cystadenoma, Serous, PTEN Phosphohydrolase, Proteins, Genes, erbB-2, Adenocarcinoma, Mucinous, Phosphoric Monoester Hydrolases, Endometrial Neoplasms, Cytoskeletal Proteins, Genes, DCC, Genes, ras, Mutation, Histological subtypes; Oncogenes; Ovarian cancer; Anatomy; Histology; Cell Biology, Female, Adenofibroma, Carcinoma, Endometrioid, Adenocarcinoma, Clear Cell
Histological subtype, Ovarian cancer, Cystadenoma, Mucinous, Humans, Histological subtypes; Oncogenes; Ovarian cancer, Neoplasms, Glandular and Epithelial, Oncogene, Ovarian Neoplasms, Retinoblastoma-Like Protein p130, Cystadenoma, Serous, PTEN Phosphohydrolase, Proteins, Genes, erbB-2, Adenocarcinoma, Mucinous, Phosphoric Monoester Hydrolases, Endometrial Neoplasms, Cytoskeletal Proteins, Genes, DCC, Genes, ras, Mutation, Histological subtypes; Oncogenes; Ovarian cancer; Anatomy; Histology; Cell Biology, Female, Adenofibroma, Carcinoma, Endometrioid, Adenocarcinoma, Clear Cell
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