
To locate the region responsible for nuclear localization of protein sAC.The eukaryotic expression vector of vairous sAC deletion mutants were transfected into Hela cells. The localization of each mutant was observed using confocal microscope.For some mutants, the localization of sAC changed. Deletion of some region made it unable to locate in the nuclear.It is possible to figure out that the nucleotide region (739-1038 and 1045-1261) take charge of nuclear localization of sAC.
Male, Microscopy, Confocal, Diabetes Mellitus, Type 2, Humans, Nuclear Proteins, Female, Genetic Predisposition to Disease, Genetic Testing, Polymorphism, Single Nucleotide, Adenylyl Cyclases
Male, Microscopy, Confocal, Diabetes Mellitus, Type 2, Humans, Nuclear Proteins, Female, Genetic Predisposition to Disease, Genetic Testing, Polymorphism, Single Nucleotide, Adenylyl Cyclases
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
