[Molecular biology advance in the Rh blood group system].

descriptionPublicationkeyboard_double_arrow_right Article 10 Mar 2006Journal:Fa yi xue za zhi, volume 21 (issn: 1004-5619,

Authors: Zhi-gang, Sun; Mei, Ding; Bao-jie, Wang;

pmid: 15895812

[Molecular biology advance in the Rh blood group system].

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Abstract

The Rh blood group system is one of the most complex of the known human blood group polymorphisms, including above 45 blood group antigens. Considerable progress has been made in our understanding of the molecular basis of Rh in the past 10 years. The bases of Rh inheritance, RH gene and its evolution, the structure and function of Rh complex, as well as nonerythroid Rh homolog, have been determined. Further improvements have been made in the technology of Rh genotyping. The review provides an update on the advance of Rh blood group to give information in the practice of forensic science.

Related Organizations

China Medical University
China (People's Republic of)

Keywords

Polymorphism, Genetic, Rh-Hr Blood-Group System, Genotype, Mutation, Blood Group Antigens, Humans, Blood Proteins, Forensic Medicine, DNA Fingerprinting, Molecular Biology

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