Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets.
Copyright policy )Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets.
A simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 287 nm for gatifloxacin tablet solutions. The linearity range was found to be 4.0-14.0 microg/mL for gatifloxacin. It was also found that the excipients in the commercial tablets did not interfere with the method.
Gatifloxacin, statistical analysis, Anti-Infective Agents, gatifloxacin, quinoline derived antiinfective agent, tablet formulation, drug determination, reproducibility, correlation coefficient, Ultraviolet, excipient, analytic method, accuracy, Reproducibility of Results, Reference Standards, calibration, ultraviolet spectrophotometry, Spectrophotometry, validation process, Calibration, linear regression analysis, Spectrophotometry, Ultraviolet, aqueous solution, Fluoroquinolones, Tablets
Gatifloxacin, statistical analysis, Anti-Infective Agents, gatifloxacin, quinoline derived antiinfective agent, tablet formulation, drug determination, reproducibility, correlation coefficient, Ultraviolet, excipient, analytic method, accuracy, Reproducibility of Results, Reference Standards, calibration, ultraviolet spectrophotometry, Spectrophotometry, validation process, Calibration, linear regression analysis, Spectrophotometry, Ultraviolet, aqueous solution, Fluoroquinolones, Tablets
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