[Expression of SSX2 gene in human urologic neoplasms].

Peng, Du; Li-zhang, Yu; Ming, Ma; Lin, Geng; Xiao-song, Wang; Dian-qi, Xin; Yan-qun, Na

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Article . 2006

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[Expression of SSX2 gene in human urologic neoplasms].

descriptionPublicationkeyboard_double_arrow_right Article 20 Nov 2006Journal:Zhonghua wai ke za zhi [Chinese journal of surgery], volume 43 (issn: 0529-5815,

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Authors: Peng, Du; Li-zhang, Yu; Ming, Ma; Lin, Geng; Xiao-song, Wang; Dian-qi, Xin; Yan-qun, Na;

pmid: 15854347

[Expression of SSX2 gene in human urologic neoplasms].

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Abstract

To investigate the expression of SSX(2)gene in human renal cell carcinoma and urinary transitional cell carcinoma.Reverse-transcription polymerase chain reaction (RT-PCR) was used for detecting SSX(2) gene in the specimens from renal cell carcinoma (n = 26), urinary transitional cell carcinoma (n = 27) and in 15 specimens taken from the tumor surrounding tissues.Positive expression of SSX(2) gene at mRNA was detected in 69% renal cell carcinomas (18/26), in 81% urinary transitional cell carcinomas (22/27). The mRNA of SSX(2) was not detected in the 15 specimens from tumor surrounding tissues.The SSX(2) gene is highly expressed in human renal cell carcinoma and urinary transitional cell carcinoma.

Related Organizations

Peking University
China (People's Republic of)
Peking University First Hospital
China (People's Republic of)

Keywords

Adult, Aged, 80 and over, Male, Carcinoma, Transitional Cell, Urethral Neoplasms, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression, Middle Aged, Kidney Neoplasms, Neoplasm Proteins, Repressor Proteins, Humans, Female, RNA, Messenger, Carcinoma, Renal Cell, Aged

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