This review introduced the recent research progress on transgenic methods and system of receptor in soybean. The major obstacles of genetic transformation in soybean and possible approach for solving the problem were also discussed. Cotyledon node via Agrobacterium tumefaciens-mediated and immature cotyledon via particle bombardment were thought to be the efficient systems of genetic transformation. Three problems existed in genetic transformation of soybean. The first one was that the system of tissue culture needs to be further improved. The second was that efficiency of genetic transformation was still low and difficult to be repeated. The last one was that restricted genotypes of soybean have been transformed successfully as a receptor. The path of solving these problems need to set a new and high efficient system for tissue culture in soybean. Also the number of target gene to be transformed will be increased from single gene to several genes at same time.