The aim of this study was to evaluate the effectiveness of non-penetrating deep sclerectomy with SK-GEL implant in the patients with pseudoexfoliation glaucoma.Non-penetrating deep sclerectomy with SK-GEL implant was performed in 5 eyes of 5 patients aged 65 to 78 (mean age 73 years +/- 5.4). Pseudoexfoliation glaucoma was recognized in all patients. In spite of the intensive pharmacological and laser treatment, sufficient reduction of an intraocular pressure was not obtained. The intraocular pressure before the surgery ranged between 24 and 43.4 mmHg (mean 31 mmHg +/- 7.6). Follow-up period lasted from 36 to 53 days (mean 46 days +/- 7.7).After the surgery, reduction of the intraocular pressure was observed in all subjects. At the moment of discharge from hospital the intraocular pressure ranged from 12 to 26 mmHg (mean 19.6 mmHg +/- 5.12), and at the last control appointment--from 14 to 16 mmHg (mean 14.9 mmHg +/- 0.72).Non-penetrating deep sclerectomy with SK-GEL implant can be taken into consideration, while planning glaucoma surgery in the patients with pseudoexfoliation syndrome.