
The study was designed to investigate the influence of hydroxyurea (HU) treatment on PRV-1 expression. Eighteen newly diagnosed patients with essential thrombocythemia (ET) or polycythemia vera (PV) were included. HU significantly increased PRV-1 gene expression in the early stage of treatment.
Aged, 80 and over, Male, Isoantigens, Membrane Glycoproteins, Platelet Count, Reverse Transcriptase Polymerase Chain Reaction, Receptors, Cell Surface, Middle Aged, GPI-Linked Proteins, Up-Regulation, Computer Systems, Humans, Hydroxyurea, Female, RNA, Messenger, Polycythemia Vera, Biomarkers, Aged, Thrombocythemia, Essential
Aged, 80 and over, Male, Isoantigens, Membrane Glycoproteins, Platelet Count, Reverse Transcriptase Polymerase Chain Reaction, Receptors, Cell Surface, Middle Aged, GPI-Linked Proteins, Up-Regulation, Computer Systems, Humans, Hydroxyurea, Female, RNA, Messenger, Polycythemia Vera, Biomarkers, Aged, Thrombocythemia, Essential
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