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Haematologica
Article . 2006
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The effects of hydroxyurea on PRV-1 expression in patients with essential thrombocythemia and polycythemia vera.

Authors: Peter, Johansson; Anne, Ricksten; Carina, Wasslavik; Berit, Johansson; Björn, Andréasson;

The effects of hydroxyurea on PRV-1 expression in patients with essential thrombocythemia and polycythemia vera.

Abstract

The study was designed to investigate the influence of hydroxyurea (HU) treatment on PRV-1 expression. Eighteen newly diagnosed patients with essential thrombocythemia (ET) or polycythemia vera (PV) were included. HU significantly increased PRV-1 gene expression in the early stage of treatment.

Keywords

Aged, 80 and over, Male, Isoantigens, Membrane Glycoproteins, Platelet Count, Reverse Transcriptase Polymerase Chain Reaction, Receptors, Cell Surface, Middle Aged, GPI-Linked Proteins, Up-Regulation, Computer Systems, Humans, Hydroxyurea, Female, RNA, Messenger, Polycythemia Vera, Biomarkers, Aged, Thrombocythemia, Essential

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    4
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
gold