[Expression of adrenomedullin and adrenomedullin receptor in the epiretinal membranes of proliferative vitreoretinopathy].
Copyright policy )[Expression of adrenomedullin and adrenomedullin receptor in the epiretinal membranes of proliferative vitreoretinopathy].
To investigate the expression of adrenomedullin (ADM) and ADM receptor (ADMR) in epiretinal membranes (ERM) of proliferative vitreoretinopathy (PVR).The expression of ADM and ADMR in 10 ERM were studied by in situ hybridization analysis (ISH).ADM and ADMR mRNAs were expressed in 7 of 10 specimens. The positive signals were distributed unevenly in positive cells. Some cells expressed mainly in the cytoplasm and the others expressed mainly in the nucleus.ADM and ADMR are expressed in the ERM of PVR, indicating that ADM and ADMR may play a role in the pathogenesis of PVR.
- Air Force Medical University China (People's Republic of)
- Xijing Hospital China (People's Republic of)
Adrenomedullin, Receptors, Peptide, Vitreoretinopathy, Proliferative, Humans, RNA, Messenger, Receptors, Adrenomedullin, Retina
Adrenomedullin, Receptors, Peptide, Vitreoretinopathy, Proliferative, Humans, RNA, Messenger, Receptors, Adrenomedullin, Retina
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