
Isis is developing ISIS-113715, an antisense inhibitor of the PTP1B gene, for the potential treatment of type 2 diabetes and obesity. ISIS-113715 is undergoing phase II clinical trials.
Male, Mice, Knockout, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Oligoribonucleotides, Clinical Trials, Phase I as Topic, Patents as Topic, Mice, Clinical Trials, Phase II as Topic, Diabetes Mellitus, Type 2, Animals, Humans, Female, Protein Tyrosine Phosphatases, Oligoribonucleotides, Antisense
Male, Mice, Knockout, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Oligoribonucleotides, Clinical Trials, Phase I as Topic, Patents as Topic, Mice, Clinical Trials, Phase II as Topic, Diabetes Mellitus, Type 2, Animals, Humans, Female, Protein Tyrosine Phosphatases, Oligoribonucleotides, Antisense
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 38 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
