
The concentration of lyso-PAF in serum from untreated patients with Japanese cedar pollinosis, a typical allergic disease, was significantly higher than that in healthy controls. It was also found that the lyso-PAF level in serum from Japanese cedar pollinosis significantly decreased after therapy with ketotifen, an anti-allergic drug. These results suggest that PAF might play an important role in Japanese cedar pollinosis and that the clinical effect of anti-allergic drug might be partially due to the anti-PAF action.
Adult, Male, Hypersensitivity, Rhinitis, Allergic, Seasonal, Humans, Pollen, Female, Ketotifen, Middle Aged, Platelet Activating Factor, Trees
Adult, Male, Hypersensitivity, Rhinitis, Allergic, Seasonal, Humans, Pollen, Female, Ketotifen, Middle Aged, Platelet Activating Factor, Trees
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