
pmid: 15112986
In this issue of Chemistry & Biology, Méndez and colleagues describe the sequence and organization of the chromomycin gene cluster. Unexpectedly, the arrangement is starkly different from the mithramycin biosynthetic cluster, despite similarity in the individual genes and the near identical structures of the two antibiotic aureolic acids.
Chromomycins, Antibiotics, Antineoplastic, Bacterial Proteins, Molecular Structure, Genes, Bacterial, Multigene Family, Streptomyces griseus, Plicamycin
Chromomycins, Antibiotics, Antineoplastic, Bacterial Proteins, Molecular Structure, Genes, Bacterial, Multigene Family, Streptomyces griseus, Plicamycin
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