[Basic phospholipase of Naja nigricollis venom].

C, Dumarey; D, Sket; D, Joseph; P, Boquet

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Article . 1976

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[Basic phospholipase of Naja nigricollis venom].

descriptionPublicationkeyboard_double_arrow_right Article 21 Feb 1976 French Journal:Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, volume 280

Authors: C, Dumarey; D, Sket; D, Joseph; P, Boquet;

pmid: 151

[Basic phospholipase of Naja nigricollis venom].

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Abstract

It is confirmed that N. nigricollis venom contains several phospholipases one of these is a basic phospholipase A. This enzyme is toxic for mice when injected intravenously. In vitro it reacts on egg yolk lecithin producing lysolecithin and prevents the phenomenon of blood clotting. An immunological identity has been established between this basic phospholipase and two acidic phospholipases present in the same venom.

Keywords

Lethal Dose 50, Mice, Phospholipases, Phosphatidylcholines, Animals, Rabbits, Amino Acids, Hydrogen-Ion Concentration, Snake Venoms

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